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pentobarbital will decrease the extent or outcome of parecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep an eye on.pentobarbital will minimize the extent or outcome of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar.Hypnotic doses of these barbiturates tend not to look to sub